超声与磁共振对类风湿关节炎腕手关节病变诊断价值的比较

Comparison of Ultrasound and Magnetic Resonance Imaging in the Evaluation of Hand and Wrist Joint Involvement in Rheumatoid Arthritis

目的探讨类风湿关节炎腕手部关节病变的超声和磁共振病变分布特征并比较二者的诊断价值。方法对11例类风湿关节炎患者进行腕手部超声和磁共振检查,计算两种影像方法对腕手部关节滑膜炎、骨质侵蚀和肌腱病变的检出率,以磁共振为金标准评价超声对腕手部关节各种病变的诊断效力。结果共评价腕手部103个关节和112个肌腱区域。超声和磁共振对腕手部关节滑膜炎、骨质侵蚀、肌腱病变的检出率分别为59.2%、11.7%、18.8%和62.1%、14.6%、32.1%。腕关节三种病变检出率均高于掌指关节和指间关节。腕部伸肌腱病变检出率高于屈肌腱,掌指关节屈肌腱病变检出率高于伸肌腱。与磁共振相比,超声对腕手部关节滑膜炎、骨质侵蚀、肌腱病变的诊断敏感性为92.2%、73.3%、59.5%,特异性为94.9%、97.7%、98.6%,阳性预测值为96.7%、84.6%、96.2%,阴性预测值为88.1%、95.6%、80.2%。结论类风湿关节炎腕部受累较掌指关节和近端指间关节常见,腕部伸肌腱病变较屈肌腱病变常见,掌指关节处屈肌腱病变较伸肌腱病变常见。以磁共振为对照,超声检查对腕关节各种病变诊断准确率较高,对掌指关节处伸肌腱病变诊断敏感性较低。

Objective To compare the values of ultrasound and magnetic resonance imaging （MRI） in the diagnosis of hand and wrist： joint involvement in rheumatoid arthritis （RA） patients and summarize the distribution pattern of these lesions. Methods A total of 11 RA cases were included. The detection rates of synovitis, bone erosion, and tenosynovitis of different joints were calculated based on ultrasound and MRI findings. The diagnostic efficiency of ultrasound was evaluated by using the MRI as golden standard. Results Totally 103 joints and 112 tendon areas were evaluated. The detection rates of synovitis, bone erosion, and tenosynovitis of wrist and hand joints were 59.2% , 11.7% , and 18.8% by ultrasound and 62. 1% , 14.6% , and 32. 1% by MRI. The detection rate of wrist joint was higher than metacarpophalangeal （MCP） or proximal interphalangeal （PIP） joints. The detection rate of extensor lesions was higher than that of flexor lesions at the wrist level; at the MCP level, however, the detection rate of flexor lesions was higher than that of extensor lesions. Compared with MRI, for the diagnosis of synovitis, bone erosion, and tenosynovitis, the ultrasound had a sensitivity of 92.2% ,73.3% , and 59.5% , a specificity of 94.9% , 97.7% , and 98.6% , a 84. 6%, and 96. 2%, and a negative predictive value of 88. 1%, 95.6% positive predictive value of 96.7%, and 80. 2%. Conclusions Wris! joint involvement is more common than MCP and PIP joints inw）lvement in RA patients. The tendon involvement is more common in extensor at the wrist level, while in flexor at the MCP level. Compared with MRI, the diag- nostic efficiency of uhrasound is higher for wrist lesions than for hand joints lesions. However, uhrasound is less sensitive in the diagnosis of extensor lesions at the MCP level.