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蒙特卡罗方法研究均整器对6MVX线能谱的影响 被引量:4

Monte Carlo Study of The Effect of Flattening Filter For 6 MV X Ray Spectrum
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摘要 目的:用蒙特卡罗方法计算Varian Trilogy加速器无均整器条件下6 MV X射线能谱,分析均整器对能谱的影响。方法:先用BEAMnrc分别模拟计算Varian Trilogy加速器6 MV射线在具备均整器和无均整器条件下,方野边长分别为4cm、6 cm、8 cm、10 cm、20 cm和40 cm时的相空间文件,以相空间文件为输入用BEAMDP分析光子能谱。结果:无均整器条件下光子注量增大,在光子能谱峰值附近最明显,射野边长为4 cm时去掉均整器后光子注量增加的最多为6.284倍,随着射野增大增加倍数减小,射野边长为40 cm时最小为2.398倍,无均整器条件下光子谱峰值能量降低,光子谱整体左移,平均能量明显减小。结论:去除均整器后,加速器的输出光子能谱发生较大变化,随之剂量特性发生改变,临床上可能产生一定的获益或未知情况,尚需要进一步的研究支持。 Objective:Used the Monte Carlo method to calculate 6 MV X-ray spectrum of Varian Trilogy accelerator without flattening filter, and analysis the effect of flattening filter for 6 MV X ray spectrum. Methods:First, simulated the 6-MV X ray phase space file ofa Varian Trilogy linear accelerator with and without flattening filter by the Monte Carlo code BEAMnrc. The field sizes used in this study were 4 cm,6 cm,8 cm, 10 cm,20 cm and 40 cm. Made the phase space file as input file to analyze the photon energy spectrum by the BEAMDP. Results:For the accelerator without flattening filter, the photon fluence was in- creased, it was obvious near the spectrum peak, it was increased 6.284 times when the field size was 4 cm, the increasing trend was decreased with the field size increased,when the field size was 40 cm the increased time was least was 2.398.In the condi- tion of without flattening filter the photon energy spectrum peak energy is reduced, the photon energy spectrum moved to the left and the average energy was significantly reduced. Conclusions: After removing flattening filter, the photon energy spectrum changed greatly, the dose characteristics changed subsequently and it may has some benefits or some unknown situations in clin ical treatment. As well as needed to further research to support.
出处 《中国医学物理学杂志》 CSCD 2014年第1期4617-4621,共5页 Chinese Journal of Medical Physics
关键词 蒙特卡罗方法 VarianTrilogy直线加速器 均整器 X线能谱 monte carlo method varian trilogy linear accelerator flattening filter X-ray spectrum
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  • 1吕庆文,陈超敏,周凌宏,李树祥,林世寅.精确放射治疗技术的现状与发展[J].中国医学物理学杂志,2005,22(1):373-375. 被引量:10
  • 2Xiao-KangZheng Long-HuaChen XiaoYan Hong-MeiWang.Impact of prolonged fraction dose-delivery time modeling intensity-modulated radiation therapy on hepatocellular carcinoma cell killing[J].World Journal of Gastroenterology,2005,11(10):1452-1456. 被引量:6
  • 3刘秀珍.高能电子束的物理特点及其临床应用注意事项[J].北京生物医学工程,2006,25(5):559-560. 被引量:2
  • 4Ahmed RS,Kim RY.IMRT dose escalation for positive para-aortic lymph node in patients with locally advanced cervical cancer while reducing dose to bone marrow and other organs at risk[J].Int J Radiat Oncol Biol Phys,2004,60:505.
  • 5Thames HD,Withers HR,Peters LJ,et al.Changes in early and late radiation responses with altered dose fractionation:Implications for dose-survival relationships[J].Int J Rddiat Oncol Biol Phys,1982,8:219.
  • 6Dale RG.The application of the linear-quadratic dose-effect equation to fractionated and protracted radiotherapy[J].Br J Radiol,1985,58:515.
  • 7Mu X,Loefroth P-O,Karlsson M,et al.The effect of fraction time in intensity modulated radiotherapy:Theoretical and experimental evaluation of an optimisation problem[J].Radiother Oncol,2003,68:181.
  • 8Fowler JF,Welsh JS,Howard SP.Loss of biological effect in prolonged fraction delivery[J].Int J Radiat Oncol Biol Phys,2004,59:242.
  • 9Harald Paganetti PHD.Changes in tumor cell response due to prolonged dose delivery times in fracfionated radiation therapy[J].Int J Radiation Oncology Biol Phys,2005,63:892.
  • 10Verhey LJ.Physical considerations in the use of intensity modulated radio therapy to produce three-dimensional conformal dose distributions[J].J Jpn Soc Ther Radiol Oncol,2000,12:191.

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  • 1CHANE E L, CULLIP T J, GABRIEL T A. A Monte Carlo study of accelerator head scatter[J]. Med Phys, 1994, 21(9): 1383-1390.
  • 2FIX M K, STAMPANONI M, MANSER P, et al. A multiple source model for 6 MV photon beam dose calculations using Monte Carlo [J]. Phys Med Biol, 2001, 46(5): 1407-1427.
  • 3KRAGL G, BALER F, LUTZ S, et al. Flattening filter free beams in SBRT and 1MRT: dosimetric assessment of peripheral doses [ J ]. Meal Phys, 2011,21(2): 91-101.
  • 4KRY S F, VASSILIEV O N, MOHAN R. Out-of-field photon dose following removal of the flattening filter from a medical accelerator[J]. Phys Med Biol, 2010, 55(8): 2155-2166.
  • 5O'BRIEN P F, GILLIES B A, SCHWARTZ M, et al. Radiosurgery with unflattened 6 MV photon beams [J]. Med Phys, 1991, 18(3): 519-521.
  • 6CASHMORE J. The characterization of unflattened photon beams from a 6 MV linear accelerator[J]. Phys Med Biol, 2008, 53(7): 1933-1946.
  • 7VASSILIEV O N, TITT U, PONISCH F, et al. Dosimetric properties of photon beams from a flattening filter free clinical accelerator[ J ].Phys Med Biol, 2006, 51(7): 1907-1917.
  • 8VASSILIEV O N, TITT U, STEPHEN F, et al. Monte Carlo study of photon fields from a flattening filter-fi'ee clinical accelerator[J]. Med Phys, 2006, 33(4): 820-827.
  • 9MESBAHI A, NEJAD F S. Monte Carlo study on a flattening filter- free 18 MV photon beam of a medical linear accelerator[ J ]. Radiat Med, 2008, 26(6): 331-336.
  • 10MESBAH A. Dosimetric characteristics of unflattened 6 MV photon beams of a clinical linear accelerator: a Monte Carlo study IJ ]. Appl Radiat lsot, 2007, 65(9): 1029-1036.

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