摘要
目的:确定单片MRI测量中国人体内脏脂肪含量的最优位置。方法:以51名健康中国人(男性27名,年龄28.89±16.56岁,BMI为23.19±3.08;女性24名,年龄47.33±19.06岁,BMI为22.38±2.53)为研究对象,采用腹盆腔连续1 cm厚MRI扫描的方法,获得精确的内脏脂肪体积。以第4-5腰椎间隙水平面作为参照平面,将其下7 cm到其上15 cm范围内每一张MRI影像中的内脏脂肪面积和总的腹盆腔内脏脂肪体积进行Pearson相关分析、偏相关分析和多元逐步回归分析。结果:男性在参照平面上10 cm,女性在参照平面上8 cm处的内脏脂肪面积与总内脏脂肪体积相关性最强(相关系数分别为0.982和0.938,P<0.01)。用两个最佳预测体积的断面作为自变量所建立的预测内脏脂肪含量的回归方程为:V(cm3)=404.421+22.576×Area+8(女性,R2=0.88,SEE=254.12 cm3);V(cm3)=273.011+23.64×Area+10(男性,R2=0.964,SEE=216.28 cm3)。结论:采用单片MRI面积分析中国人体内脏脂肪时的最佳测量位置是第4-5腰椎平面上10 cm(男性)和其上8cm平面(女性)。
Objective: To determine the optimal site of evaluating visceral adipose tissue of Chinese. Methods: 51 Chinese sub- jects (males, n=27, 28.89±16.56 years old BMI: 23.19±3.08; and females, n=24, 47.33±19.06 years old, BMI: 22.38±2.53) with no medical disease underwent consecutive MRI examination for quantifying visceral adipose tissue volume (lcm image thick- ness). Visceral adipose tissue (VAT) areas of 23 MR images from 7 cm below to 10 cm above the L-L5 plane were measured. Correlation between VAT area and volume was determined by Pearson Correlation Coefficient, partial correlation analysis and multivariate regression analysis. Results: visceral adipose tissue area at 10 cm (male) and 8 cm (female) above the L4-L5 level showed the strongest correlation with VAT volume(r=0.982, r=0.938, respectively, P〈0.01). Simple regression with the optimal VAT areas as independent variable and VAT volume as dependent variable are V(cm3)=404.421+22.576×Area+8(female: R2=-0. 88, SEE=254.12 cm3) ;V (cm3)=273.01 l+23.64xArea×0 (male: R2=0.964, SEE=216.28 cm3).Conclusions: The optimal site to measure visceral adipose tissue volume is 10 cm (male) and 8 cm (female) above the L4-L5 level.
出处
《中国医学物理学杂志》
CSCD
2014年第1期4704-4708,共5页
Chinese Journal of Medical Physics
基金
清华大学自主科研计划资助(2012THZ02177)