云芝胞内糖肽胶囊联合光动力治疗男性尿道尖锐湿疣临床观察及基因型检测

Polystictus glycopeptide capsules pins photodynamic therapy for male urethral condyloma acuminatum： clinical observations and gene detection

予26例男性尿道尖锐湿疣患者云芝胞内糖肽胶囊口服4周加光动力治疗1～5次,首次治疗前取疣体组织检测人乳头状病毒（HPV）基因型.疣体完全脱落,随访6个月,1例复发;24例检出HPV DNA基因型,高危型感染阳性率46.2％;存在高危型/低危型混合交叉感染,低危型HPV6多重感染率23.1％,高危型多重感染率58.3％;高危型HPV16、HPV31、HPV58和HPV6、HPV11均以混合感染存在.

A total of 26 male patients with urethral condyloma acuminatum took Polystictus glycopeptide capsules orally for 4 weeks plus 1-5 sessions of photodynamic therapy. Prior to the first session, human papilloma virus （HPV） genotype of wart tissue was detected. Verrucous body fell off completely. The follow-up period was 6 months. There was one recurrent case. And 24 cases had HPV genotype DNA. The positive rate of high-risk infection was 46. 2% ; the high/low-risk mixed type cross infection was present. The muhiple HPV6 low-risk infection rate was 23.1% and multiple high-risk infection rate 58.3% ; high- risk type HPV16, HPV31, HPV58 and HPV6, HPV11 were all of mixed types.