天麻钩藤饮对肝阳上亢证急性脑梗死患者同型半胱氨酸的影响及临床疗效观察

Influence of Tianma Gouteng Yin on Homocysteine and Its Clinical Efficacy on Patients with Liver Yang Hyperactivity Syndrome of Acute Cerebral Infarction

目的:观察天麻钩藤饮对肝阳上亢证急性脑梗死患者同型半胱氨酸的影响及临床疗效。方法:选择符合中西医诊断标准及辨证属肝阳上亢证的急性脑梗死病人120例,随机分治疗组和对照组各60例,治疗组用天麻钩藤饮加常规西医治疗法,对照组用常规西医治疗法,3周后评定疗效。比较两组治疗前后中医证候积分,神经功能缺损评分及同型半胱氨酸水平。结果:治疗组在临床疗效,调节同型半胱氨酸方面优于对照组(P<0.05)。结论:天麻钩藤饮能提高肝阳亢上证脑梗死的临床治疗效果,降低同型半胱氨酸水平,可用于急性脑梗死的防治。

Objective：To observe the effect of Tianma Gouteng Yin （TMGTY）on homocysteine in patients with liver yang hyperactivity syndrome of acute cerebral infarction and its clinical efficacy. Methods ： 120 patients of acute cerebral infarction belonging to liver yang hyperactivity syndrome and consistent with the traditional Chinese and Western medicine diagnosis standard were randomly divided into the treatment group and the control group with 60 cases in each. The treatment group were treated with TMGTY and routine western medicine therapy, while the control group were treated with routine western medicine therapy only, evaluating the curative effect 3 weeks later. The TCM syndrome score, the Neural function defect score and the Homocysteine level before and after treatment between the two groups were compared. Results： The treatment group was better than the control group in the clinical efficacy and in regulating the Homocysteine level. Conclusion：TMGTY improves the clinical treatment effect of cerebral infarction belonging to liver yang hyperactivity syndrome and reduces the Homocysteine level and can be used for the prevention and treatment of acute cerebral infarction.