148例新生儿体表先天畸形发病情况分析

Analysis of 148 cases of neonatal onset congenital malformation of body surface

目的了解先天性畸形发病情况及其影响因素，探讨畸形发生的原因和预防措施。方法对2003年1月～2012年12月10年间，对长治医学院附属和济医院出生的7987例新生儿中的148例体表先天畸形儿的发病情况及其相关因素进行回顾性分析。结果本组体袁先天畸形发生率为1．85％；神经系统先天畸形居首；其次是骨骼系统和颌面五官系统。1〉35岁产妇先天畸形儿发生率显著高于〈35岁者（P〈0．01）；农村先天畸形发生率高于城市（P〈0．叭）。结论应重视先天畸形的防范措施，加强优生宣教，尤其是农村地区，加强孕期畸形儿筛查，特别是高龄孕妇，做到早发现、早处理，以提高产前诊断率，减少出生缺陷。

Objective： To understand the factors of congenital malformation incidence and influence of deformity, explore the cause and preventive measures. Methods： On the 2003 January - 2012 December 10 years, the incidence of 7987 cases of neonatal Heji Hospital Affiliated to Changzhi Medical College was born in 148 cases of congenital malformation of body surface and its related factors were analyzed retrospectively. Results： This group of body surface congenital malformation incidence was 1.85% ; the first is congenital anomalies of nervous system ; the second is the skeletal system and the facial features system. 35 years of age or ol- der maternal congenital deformity rate was significantly higher than that of 〈 35 years of age （ P 〈 0.01 ） ; rural congenital malfor- mation incidence was higher than that of city （ P 〈 0.01 ）. Conclusion ： Attention should be paid to congenital malformation of the preventive measures, strengthening health education. Strengthen the malformation screening during pregnancy, especially in rural areas. Especially pregnant women, early detection, early treatment, to improve the prenatal diagnosis rate, reduce the birth de-fect.