乳腺癌术后辅助治疗疗效分析

An Analysis of Effect Postoperative Adjuvant Therapy for Breast Cancer

目的 探索乳腺癌根治术后患者病期、淋巴结情况及治疗方法对生存率的影响。方法对比分析我科收治的乳腺癌术后Ⅱ期 110例和Ⅲ期 90例 ,采用术后放疗、术后化疗及术后放疗加化疗进行治疗。结果 Ⅱ期和Ⅲ期乳腺癌患者术后放疗、术后化疗 +放疗局部复发率均低于术后化疗 (P <0 0 5) ;Ⅲ期患者远处转移率术后放疗高于术后化疗或术后放疗 +化疗 (P <0 0 5) ;Ⅱ期乳腺癌腋窝淋巴结转移数≥ 4个 ,生存率下降 ;Ⅲ期乳腺癌患者随着N的升级 ,五年生存率逐渐降低。结论 乳腺癌术后放疗可以减少局部复发率 ;Ⅲ期乳腺癌术后化疗可降低远处转移率 ;淋巴结转移数影响 5年生存率。

To study the effect of stage, Iymph nodes and therapy methods on the survival rate for breast cancer after radical operation.Methods Treatment results were compared between 110 stage Ⅱ and 90 stage Ⅲ breast cancers who received postoperative radiotherapy(RT),Chemotherapy (CT)and chemotherapy plus radiotherapy (CRT) in our department.Results The local recurrence rates for stage Ⅱ and stage Ⅲ with RT group and CRT group compared with CT group have significance ( P <0 05).Distance metastasis rates for stage Ⅲ patients with CT group and CRT group compared with CT group have significance ( P <0 05).The 5-year survival rates for patients with ≥4 positive axillarys Iymph nodes in stage Ⅱ decrease ( P <0 05),The 5-year survival rates of stage Ⅲ breast cancer declined gradually with increase of the N.Conclusion Postoperative RT of breast cancer could reduce the local recurrence rates.Postoperative CT for stage Ⅲ breast cancer could reduce distance metastasis rates.Axillarys Iymph nodes effect on the 5-year survival rates.