介入电化学治疗食管癌梗阻近期疗效观察

Observations of Recent Effect in Electrochemotheropy of Obstruction of Esophageal Carcinoma

目的 探索快速解除食管癌梗阻的新疗法。方法 X线透视引导下食管病灶腔内介入铂合金电极 ,输入一定量单项直流电的电化学疗法。结果 治疗中晚期食管癌 38例 ,CR3例( 7 9% ) ,PR2 8例 ( 73 7% ) ,NC7例 ( 18 4 % ) ,有效率 81 6%。有效者均于 3～ 7天进食即改善 ,3～14天进食提高 1～ 3个类别 (P <0 0 1) ,7～ 14天食管腔平均增宽 3 1倍 (P <0 0 1)。一次性治疗有效缓解期 1～ 6个月不等。结论 该疗法对食管癌梗阻的局部疗效快而显著 ,尤以缩窄型为佳 ,可为其快速解除梗阻较好的措施之一 ,且简便易行。

To search for a new method to release the esophageal obstruction rapidly.Methods Electrochemical therapy (EChT) was performed by inserting platinum alloy electrodes into the site of the esophageal carcinoma under x-ray guidance with direct current.Results The recent result in 38 advanced esophageal carcinomas was shown as follows:three (7 9%) of them were CR,28(73 7%)PR,7(18 4%)NC,the total effective rate was 81 6%.The esophageal obstruction was improved within three to seven days after the treatment.The meal grade was increased from one to three ranges winthin three to fourteen days ( P <0 01).The average esophageal lumen diameters of 38 cases were widened 3 1 times within seven to fourteen days ( P <0 01).The effective relief period of one-shot therapy was from one to six months. Conclusion EChT is one of the most effective methods in the treatment of advanced esophageal carcinoma,especially those of restriction type.