老年人外伤性急性颅内血肿手术预后分析

The prognosis of acute traumatic intracranial hematomas after surgery in elderly patients

目的 探讨影响老年人外伤性急性颅内血肿的手术效果的相关因素。方法 选择经过手术治疗的老年人外伤性急性颅内血肿 12 4例 ,从病人年龄、GCS评分、血肿量、手术时机、手术方式等因素分析与效果的关系。结果 患者年龄 >80a的死亡率为 5 0 .0 % ,GCS评分 3～ 8分的死亡率为 5 4.5 % ,血肿量 >10 0ml的死亡率为 75 .0 % ,手术时间 <6h的死亡率为 38.5 %。结论 患者年龄越大、GCS评分越低、血肿量越大、发病至手术时间越短者 ,其预后越差。

Objective To discuss the correlative factors which influence the effect in surgery therapy of acute traumatic intracranial hematomas in the elderly patients. Methods One hundred and twenty four elder patients undergoing operations in acute traumatic intracranial hematomas were studied, and the age of patients ,GCS, size of hematoma, suffering time ,surgery methods and so on were compared . Results The mortality in the patients >80 years old,GCS3～8, size of hematoma> 100 ml and operations within 6 hours after injury was 50.0% ,54.5%, 75.0%,38.5%,respectively . Conclusions The prognosis is poorer in patients >80 years old,and patients with lower GCS ,larger hematoma and shorter duration after injury to operation. Key words older patient craniocerebral injury intracranial hematoma mortality urokinaseduced multiple resistant mutants and the effect of CCCP on it were similar to those of clinical resistant isolates. It predicted that the active efflux mechanism of acquired multiple resistance was the same to that of intrinsic ones.