滕州市农村青壮年肺结核发病危险因素的条件logistic回归分析

Conditional Logistic regression analysis of risk factors of pulmonary tuberculosis in rural young adults of Tengzhou City

目的探讨农村青壮年肺结核发病的危险因素,为制定干预对策与措施提供依据。方法 2011年7月—2012年12月,选取滕州市新发肺结核患者121例,按照1∶1配对方法选择同一社区内与病例同性别、年龄±3岁,无严重呼吸系统疾患病史的人群为对照。进行影响肺结核患病的条件logistic回归分析。结果在α=0.05的水平上,进入多因素条件logistic回归模型的有8个因素,即接种卡介苗可降低肺结核发病危险性,OR值为0.54;经济状况差、饮酒、结核病接触史、劳动疲乏、住房类别、体重指数、外出打工易患肺结核的OR值分别为3.68、1.67、1.99、2.87、1.87、2.56和2.97。结论经济状况差、饮酒、结核病接触史、劳动易疲乏、住房通风不好、体质偏瘦、外出打工是该市农村青壮年肺结核发生的主要危险因素,卡介苗接种是降低发病的保护性因素。

[ Objective ] To investigate the risk factors of pulmonary tuberculosis （ TB ） in young adults in rural areas, and provide evidence for formulating strategies and measures. [ Methods] A total of 121 new cases of TB in Tengzhou City were selected from July 2011 to December 2012, according to 1：1 pairing method, the people from the same community with the same sex ratio and ±3 years age range of TB patients and no history of severe respiratory disease were selected as control group. Conditional logistic regression analysis was carried out on Influencing factors of pulmonary tuberculosis. [ Results] At the level of α =0.05, 8 factors were brought into the multiple conditional logistic regression model, which mean the BCG vaccination could reduce the risk of pulmonary tubercu- losis, OR value was 0.54. The OR values of poor economic conditions, drinking wine, TB exposure history, work fatigue, housing types ,body mass index and going out for work were 3.68, 1.67, 1.99, 2.87, 1.87, 2.56 and 2.97. [ Conclusion] Poor economic conditions, drinking wine, TB exposure history, work fatigue, housing types, slim physique, going out for work are the main risk factors of local young patients of TB, BCG vaccination is the protective factors against TB incidence.