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维持性血液透析患者顽固性高血压及残余肾功能的相关研究 被引量:4

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摘要 目的:探讨治疗维持性血液透析(MHD)患者的顽固性高血压,同时又能保护残余肾功能的方法。方法:50例既有顽固性高血压又有残余肾功能,且服用常规降压药效果不理想的维持性血液透析患者,随机分为两组:一组加服米诺地尔,另一组强化超滤,观察6个月,比较各组降压效果及对残余肾功能的影响。结果:基线处2组患者透析前收缩压、舒张压未见明显差异;24 h尿量未见明显差异。经过6个月的观察,两组收缩压、舒张压、24 h尿量均下降,强化超滤组24 h尿量明显低于米诺地尔组(t=25.46,P<0.05)。结论:对于有顽固性高血压的MHD患者,加用米诺地尔和强化超滤治疗均能有效控制血压,强化超滤对残余肾功能的影响较大,米诺地尔在有效降压的同时可以更好地保留残余肾功能。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2013年第12期1716-1718,共3页 Journal of Nanjing Medical University(Natural Sciences)
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