凶险型恶性疟7例的临床特点分析

Clinical analysis of 7 cases with severe falciparum malaria

目的探讨凶险型恶性疟的特征及防治措施。方法对本院收治的7例凶险型恶性疟病例临床资料进行回顾性分析。结果 7例凶险型恶性疟患者均为境外输入,有明确的疫区生活史。该类患者临床症状不典型,病情发展迅速,容易出现严重并发症,急性肾功能不全、DIC和继发细菌感染是该类患者最常见的并发症。青蒿素及其衍生物对凶险型疟疾患者疗效确切。结论加强对凶险型恶性疟疾的认识,及时有效的抗疟治疗和并发症的积极治疗是抢救这类患者的关键。

Objective To explore the characteristics of severe falciparum malaria and control measures. Methods The data of 7 severe malignant malaria cases were analyzed retrospectively. Results All the 7 severe falciparum malaria cases got the infection abroad and returned to Anhui Province with obvious life history in endemic falciparum malaria area.The symptoms of these patients were not typical but conditions developed rapidly. Patients easily got involved in severe complications. The artemisinin is effective on these patients. Conclusions Enhancing recognition of the severe malaria, anti-malaria and anti-complication early and effectively is the key to recovery for the patients.