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三阴性乳腺癌的分子生物标记的研究进展 被引量:6

Research Progress in Molecular Biomarkers of Triplenegative Breast Cancer
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摘要 Notch、Wnt和Hh信号通路均参与了三阴性乳腺癌的发生发展。Aurora激酶A、Chk1、miR-93等在三阴性乳腺癌中存在过表达,并与其预后相关,为其治疗提供了新靶点。 Abstract : Note.h, Wnt,Hh signaling pathways parlieipate in the development of triple-negative breast caner: Aurcra Kinase A ,Chkl ,miR-93 are over-expressed and correlated with prog nosis in triple-negative breast cancer,they may provide more potential therapeutie targets.
出处 《中国肿瘤》 CAS 2014年第1期53-57,共5页 China Cancer
关键词 三阴性 乳腺癌 信号通路 靶向治疗 triple-negative phenotype breast cancer signal pathway targeted therapy
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  • 1许良中,杨文涛.免疫组织化学反应结果的判断标准[J].中国癌症杂志,1996,6(4):229-231. 被引量:1365
  • 2杜长征,李惠平,马力文,付卫,王墨培,贾廷珍,赵红梅,侯宽永.中国乳腺癌患者p53表达临床生物学意义的Meta分析[J].中国癌症杂志,2005,15(6):514-517. 被引量:23
  • 3邵志敏,余科达.乳腺外科的发展趋势[J].中国普外基础与临床杂志,2007,14(3):252-254. 被引量:68
  • 4Sorlie T,Perou CM,Tibshirani R,et al.Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications[J].Proc Natl Acad Sci U S A,2001,98(19):10869-10874.
  • 5Norbeng T,Klaar S,Karl G,et al.Increased p53 mutation frequency during tumor progression results from a breast cancer cohort[J].Cancer Res,2001,61(22):8317-8321.
  • 6Dookeran KA,Dignam JJ,Ferrer K,et al.p53 as a marker of prognosis in African-American women with breast cancer[J].Ann Surg Oncol,2010,17(5):1398-1405.
  • 7Chae BJ,Bae JS,Lee A,et al.p53 as a specific prognostic factor in triple-negative breast cancer[J].Jpn J Clin Oncol,2009,39(4):217-224.
  • 8Rakha EA,El-Sayed ME,Green AR,et al.Prognostic markers in triple-negative breast cancer[J].Cancer,2007,109(1):25-32.
  • 9Geisler S,Lonning PE,Aas T,et a1.Influence of TP53 gene alterations and cerbB2 expression on the response to treatment with doxorubicin in locally advanced breast cancer[J].Cancer Res,2001,61(6):2505-2512.
  • 10Malamou-Mitsi V,Gogas H,Dafni U,et al.Evaluation of the prognostic and predictive value of p53 and Bcl-2 in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy[J].Ann Oncol,2006,17(10):1504-1511.

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