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孤立性骨髓瘤继发弥漫大B细胞淋巴瘤一例并文献复习

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摘要 目的 探讨1例骨孤立性浆细胞瘤(SPB)进展为多发性骨髓瘤(MM)后发生弥漫大B细胞淋巴瘤(DLBCL)患者的临床特点.方法 分析该患者不同时间的临床特点、病理表现和治疗经过,并复习相关文献.结果 患者SPB确诊后2年内治疗有效,病情稳定;2年后进展为MM;1年后发生DLBCL,对化疗耐药.结论 SPB在治疗过程中部分可转化为MM,但也可发生其他肿瘤.因此,在病变治疗过程中,需要及时进行活组织检查,明确病变的性质及是否发生转化.
出处 《白血病.淋巴瘤》 CAS 2013年第12期748-750,共3页 Journal of Leukemia & Lymphoma
基金 北京市自然科学基金(7132183)
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参考文献10

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