人工注射局部水囊技术辅助超声引导射频消融治疗高危部位肝肿瘤的临床研究

A clinical study of artificial injection with local water band assistance percutaneous radiofrequency ablation of high-risk parts of the small liver cancer

目的 探讨人工注射局部水囊技术辅助超声引导射频消融治疗高危部位肝肿瘤的安全性和临床疗效.方法 超声引导下用介入穿刺针从体表穿刺进入肝脏与紧要器官间隙,注入生理盐水500～1000 ml,形成人工水囊间隔带,将肝脏与邻近器官隔开,对14例患者共20个病灶行经皮超声引导射频消融治疗,术后1个月复查增强CT评价疗效.结果 1个月后肿瘤影像学评价,20个病灶中,16个完全消融,坏死率达80％.无严重并发症发生.6个月内复发2例,1年内复发3例,其中出现新病灶2例,原来坏死病灶再次强化伴CEA增高3例,全组病例目前存活9例,随访时间最长20个月,最短7个月,平均生存期10个月.结论 人工注射局部水囊技术辅助超声引导射频消融治疗高危部位肝肿瘤近期疗效确切,是一种安全、微创、有效的方法.

Objective To evaluate the safety and effectiveness of artificial injection with local water band assistance percuta- neous radiofrequency ablation of high - risk parts of the liver cancer. Methods Uhrasound-guided needle into the liver and the critical organ gap from the body surface, injected with normal saline 500-1000ml, with the formation of artificial local water band intervals, separated from the liver and adjacent organs, in 14 patients of 20 lesions with percutaneous radiofrequency ablation treatment, after 1 month review enhanced CT evaluated. Results One month after the tumor imaging evaluation,.20 lesions, 16 complete ablation, nec- rosis rate of 80%. No serious complications occurred. Relapse within 6 months in 2 cases, 3 cases of recurrence within 1 year, inclu- ding the emergence of new lesions in 2 cases, necrotic lesions reinforces the original with CEA increased three cases, all patients now survive nine cases, the longest follow-up time of 20 months, the shortest 7 months, the average survival was 10 months. Conclusions Artificial injection with local water band assistance percutaneous radiofrequency ablation of high-risk parts of the small liver cancer is a safe, minimally invasive and effective method.