冠心病与阻塞性睡眠呼吸暂停综合征患者睡眠动脉血氧减饱和度指数分析

Analysis of the arterial oxygen desaturation index of the patients with coronary heart disease and obstructive sleep apnea syndrome during sleep

目的 :探讨阻塞性睡眠呼吸暂停综合征 (OSAS)与冠心病 (CHD)发生、发展的关系。方法 :通过使用多导睡眠仪对 38例单纯 OSAS患者、2 2例 CHD并发 OSAS患者进行氧减饱和度指数 (ODI)监测分析。结果 :CHD并发 OSAS组的 ODI最高为 50 .55± 1 8.2 5,较 OSAS组 (38.65±1 4.2 8)明显增高 (P <0 .0 5) ,且与呼吸紊乱指数呈明显的正相关 (P <0 .0 1 )。结论 :OSAS并发CHD组夜间缺氧程度最重、最频繁 ,OSAS患者

Objective:To study the relation between the obstructive sleep apnea syndrome (OSAS) and coronary heart disease.Although there was some study, the exact mechanism about how the former develops to the latter was not completely known.Method:This study monitored 38 patients with simple OSAS and 22 OSAS patients complicated with coronary heart disease by analyzing their oxygen desaturation index (ODI) and apnea/hypopnea index (AHI).Result:The study explored that the ODI of the patients complicated with coronary heart disease was 50.55 ± 18.25 ,which was greater than that ( 38.65 ± 14.28 ) of the OSAS patients (P< 0.05 ).In addition,there was a significant positive correlation (r= 0.451 ,P< 0.01 ) between ODI and AHI.Conclusion:Hypoxia of the OSAS patients complicated with coronary heart disease is most serious and frequent during sleeping.The occurrence of coronary heart disease in SOAS patients may result from long term hypoxia.