腹膜后副神经节瘤25例临床分析

Clinical analysis of retroperitoneal paraganglioma： a report of 25 cases

目的 探讨腹膜后副神经节瘤的诊断和治疗,提高其早期诊断及手术切除率.方法 对25例原发性腹膜后副神经节瘤患者行手术治疗.结果 25例中术后病理诊断良性肿瘤19例,恶性肿瘤为6例,完全切除19例,大部切除3例,其中围手术期死亡l例,无法切除3例,术后复发3例中再手术2例肿瘤完全切除,1例放弃手术.结论 腹膜后副神经节瘤早期临床表现缺乏特异性,诊断目前主要靠影像学检查,围手术期处理至关重要,手术完整切除仍是治疗的主要手段,对复发性肿瘤应争取再次手术.

Objective To study the diagnosis and treatment of retroperitonea paraganglioma, and improve the early diagnosis and operation resection rate. Methods A total of 25 cases of primary retroper- itoneal paraganglioma underwent surgical treatment. Results All 25 cases were pathologically diagnosed, including 19 cases of benign tumor,6 cases of malignant tumor. The complete resection was operated in 19 cases and major resection in 3 cases. One patient died during the perioperative period. Three cases of tumor could not be resected,The tumor relapsed in 3 cases ,2 of them had another complete resection and 1 pa- tients gave up the operation. Conclusion The early clinical manifestations of retroperitoneal paraganglio- ma lack specificity and the diagnosis mainly depends on imaging examination. Perioperative management is crucial. The complete resection remains to be the main measure and the recurrent tumors should undergo a secondary operation.