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CD44v6基因在子宫颈癌中的表达意义 被引量:7

Significance of expression of CD44-v6 in human cervical cancer
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摘要 目的 探讨 CD44 v6基因在子宫颈癌组织中的表达情况及其临床意义。方法 用免疫组织化学 S- P法 ,检测 5 6例子宫颈鳞癌 ,32例子宫颈腺癌中 CD44 v6蛋白的表达情况并分析相关的临床病理因素。结果 CD44 v6表达与宫颈癌组织学类型无关 ;无论子宫颈腺癌或鳞癌 ,淋巴结转移组中 CD44 v6阳性表达明显高于无淋巴结转移组 (P<0 .0 5 ) ;CD44 v6表达与子宫颈癌临床分期、病理分级、病灶大小无关 (P>0 .0 5 )。结论  CD44 v6在子宫颈癌淋巴结转移及癌细胞分化过程中起着重要作用 ,对早期预测癌细胞的转移潜能、判断子宫颈癌预后具有重要的临床意义。
作者 柳洲 陈惠祯
出处 《实用肿瘤杂志》 CAS 北大核心 2001年第1期49-51,共3页 Journal of Practical Oncology
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