亚低温治疗重型颅脑损伤的临床分析

Clinial analysis of mild hypothermia in patients with severe head injury

目的探讨亚低温对重型颅脑损伤的脑保护作用及临床疗效。方法回顾性分析我院收治的251例特重型颅脑损伤患者,常规治疗组182例和亚低温治疗组69例。亚低温治疗组均在受伤后24 h内行亚低温治疗,比较两组的手术疗效及对患者预后的影响。结果与常温治疗组比较,亚低温治疗组恢复良好率显著提高,病死率显著降低,预后改善显著,且并发症无明显增加。结论在常规治疗的基础上加用亚低温治疗特重型颅脑外伤,可以明显改善患者的预后;能显著降低特重型颅脑损伤的死残率。

Objective To study clinical effect of mild hypothermia in patients with severe head injury. Methods A total of 251 patients with severe head injury at our hospital according to treatment eonditions divided into the mild hypothermic group（69 cases） and the control group（ 182 cases）. Mild hypothermia was induced within 24 hours of injury. On the basis of the conventional treatment,the treatment group for mild hypothermia therapy, Simple surgical treatment group were compared and the impact on prognosis were analyzed. Results In comparison with the control group, the good recovery rate was significantly increased, the mortality was reduced and the prognos was improved significantly for patients in the mild hypothermia group. Yet the complications were not increased significantly. Conclusion Based on the conventional treatment , the treatment of mild hypothermia is safe and effective for preventing brain damage on patients with severe head injury, as well as reducing mortality and improving the prognosis.