神经质程度和月经周期对女性主观情绪和生理反应的影响

Effects of Menstrual Cycle and Neuroticism on Emotional Responses of Healthy Women

分别选取两组神经质程度高、低女性16名和25名,考察两组被试在月经周期不同阶段(经期、卵泡晚期、黄体中晚期)的激素(雌二醇、孕酮)波动以及观看情绪视频(中性、搞笑、悲伤、愤怒)的主观情绪感受和生理反应的差异。结果显示高神经质女性在月经周期中对负性情绪视频的主观情绪和生理反应变化明显,黄体中晚期对愤怒视频主观情绪体验更低,对悲伤视频生理反应更小,而低神经质女性的情绪反应不受月经周期影响。研究表明高神经质女性的情绪反应更易受月经周期影响,这可能与其对孕酮水平波动的敏感性高有关。

Women experience dramatic fluctuations in progesterone and estradiol during menstrual cycles, which will likely influence their mood. The subjective experience and neural responses towards emotional stimuli of women who suffer from premenstrual syndrome （PMS） seemed to differ across menstrual cycles. However, it remains unknown that if women without PMS will have mood swings during a menstrual cycle. Additionally, some studies argued that neuroticism was closely associated with PMS. But it is still unclear whether neurotic women without PMS would have different responses towards emotional stimuli in different phases of menstrual cycle like women with PMS. The current study was designed to investigate the influence of neuroticism on the subjective experience and physiological responses towards emotional stimuli in the non-PMS sample across amenstrual cycle. We hypothesized that neurotic women would have more intense subjective experience and physiological responses towards emotional stimuli, especially in the premenstrual phase. Forty-one right-handed female with regular menstrual cycle took part voluntarily in this within-subject study. The results of Eysenck Personality Questionnaire （EPQ） divided this sample into the high neuroticism group （HN group, n = 16） and the low neuroticism group （LN group, n = 25）. Each participant performed a film watching and evaluating task three times during mid-late luteal, menstrual and late ovulation phases respectively. 12 film clips were selected. Among them, nine 3-minute film clips were supposed to evoke amusement, sadness, and anger （3 clips for each emotion） and 3 film clips were neutral. For each visit, the participant would watch 4 film clips randomly selected from 12 film clips, one for each emotion and a neutral one, and the order of clips was counter-balanced. Each time the participant came to the lab and relaxed for 3 minutes （baseline）, then she watched a film clip and completed the emotion inventory to evaluate how they felt about the clip. She was then asked to relax for another 3 minutes to recover from the emotional arousal. The physiological responses including heart rate, galvanic skin response （GSR） and respiratory rate were recorded at this time. This procedure was repeated until all 4 film clips （one for each emotion and a neural film） were viewed. The results showed that there was a significant interaction between menstrual cycle and group membership for self-reported anger and disgust in response to angry films. The HN group scored lower in self-reported anger and disgust than the LN group only in the mid-late luteal phase, and there was a significant effect of menstrual cycle in HN group but not in LN group for self-reported anger. We calculated rate of change for the analysis of heart rate and found a significant effect of menstrual cycle for the HN group but not for the LN group when they were watching neutral and sad films. The rate of change in the LN group was significantly greater than that in the HN group in the mid-late luteal phase, but not in the other two phases. We also calculated rate of change for the analysis of respiration rate and found that the change of rate is significantly greater for the HN group than that for the LN group, but only in the menstrual phase. Taken together, the subjective experience and physiological responses towards negative emotion during menstrual cycles seem to be more influential for neurotic women than for those who are low in neuroticism. Furthermore, neurotic women seemed to be less vulnerable to negative emotion during their mid-late luteal phase than during other phases. Sensitive response of neurotic women to the fluctuation of progesterone during menstrual cycles may be one of the reasons that account for their mood change.