中药防治放射性食管炎的临床疗效分析

目的评估中药对急性放射性食管炎（RE）的防治作用。方法100例肺癌患者随机分为治疗组和对照组。治疗组52例患者口服中药治疗，对照组48例患者口服西药治疗，所有患者均进行同步放化疗。观察患者近期疗效并评估患者食管急性不良反应。结果治疗组和对照组I度和Ⅱ度RE发生率分别为38．5％与58．0％，两组患者比较有显著性差异（P〈0．05）。结论中药防治放射性食管炎安全有效。在防治1～2级放射性食管炎方面优于西药。

Objective To assess the clinical effectiveness of Chinese medicines for prevention and treatment of acute radiation esophagitis （RE）.Methods 100 patients with lung cancer receiving radiotherapy were randomly divided into the treatment group and the control group.52 patients in the treatment group took orally the Chinese medicines and 48 patients in the control group took Western medicines.All patients with lung cancer were treated with radiotherapy and concurrent chemotherapy.The recent clin- ical effect and RE were observed and compared between two groups.Results The incidence rates of grade 1,2 RE in the treat- ment group and control group were 38.5% vs.58.0% respectively.There were a significant difference in the incidence rates of grade 1,2 RE （P 〈 0.05）.Conclusions Chinese medicines are effective and Safe in preventing and treating RE,and superior to Western medicines in preventing and treating grade 1~2 RE.