依那普利对高血压病患者血液流变学的影响

目的探讨依那普利对高血压病患者血液流变学的影响。方法32例高血压病患者均口服依那普利片5mg，每日2次，4周为一疗程，服药期间停用其它血管活性药物，治疗前后测量血压、全血比黏度和血浆比黏度。结果32例患者应用依那普利治疗1周后收缩压、舒张压和平均动脉压均显著降低（P〈0．001）；全血比黏度高切变值和低切变值均有明显降低（P〈0．01）。结论依那普利既有良好的降压作用，又能降低血液高黏滞状态。

objective to investigate the enalaprilat affect hypertension patient blood theology.Methods 32 patients with essential hypertension were oral enalaprilat 5 mg,Bid,4 weeks for a period of treatment,medication during outage other vascular active drugs,measure blood pressure before and after the treatment,whole blood viscosity and plasma viscosity.Results 32 cases of patients with one week after application of enalaprilat systolic pressure,diastolic pressure and mean arterial pressure were significantly lower （P 〈 0.001）;Than whole blood high shear viscosity and low shear values were significantly decreased （P 〈0.01）.Conclusion enalaprilat is both a good antihypertensive effect,and can reduce high blood viscosity state.