抗菌肽的来源及应用

Antibacterial Peptides: Origns and Applications

抗菌肽是广泛存在于自然界生物中的一类多肽物质,作为生物机体的第1道防线能够抵抗病原体的侵害。抗菌肽具有抗细菌、真菌、病毒,抑杀癌细胞等多种生物活性,且不易产生抗药性。抗菌肽的这些特性使其最有希望代替传统抗生素。本文总结了抗菌肽的来源、特性及其应用前景,并阐述了目前在抗菌肽研究和应用中存在的主要问题。

The antibacterial peptides are a class of peptides that widely exist in many creatures in nature, which serve as the first line of defense against invasion pathogenic organisms. The antibacterial peptides have many biological activities, such as antibiosis, anti-fungi, anti-virus, killing the cancer cells and little or no drug re- sistant. All of these beneficial physiological activities make them a prior choice to substitute traditional antibiot- ics. In this article, we reviewed the origns, characteristics and application prospects of antibacterial peptides, and the problems in research and application of antibacterial peptides were also reviewed.