安徽某三甲医院戊型肝炎流行病学特点分析

Epidemiological characteristic analysis of hepatitis E

目的 分析戊肝流行情况与趋势,探讨流行规律,为制定防治措施提供实验的依据.方法 回顾性收集安徽医科大学第一附属医院2010年1月1日-2012年12月31日戊肝资料并对其流行特征进行分析.结果 安徽医科大学第一附属医院2010年1月1日-2012年12月31日共检测血清戊肝抗体标本7 903份,其中抗-HEV-IgG阳性832份,检测阳性率为10.53%,抗-HEV-IgM阳性409例,检测阳性率为5.18%.2010、2011和2012年戊肝患者占病毒性肝炎患者的比例分别为2.39%、3.67%、3.14%.20岁以下人群血清抗-HEV-IgM阳性率〈1%.40～60岁年龄段患者占全部戊肝患者的61.8%.3年血清抗-HEV-IgM阳性男女比分别为3.93：1,4.00∶1,3.57：1.结论该研究资料提示20岁以下人群中戊肝阳性率极低,男性和40～60岁人群具有较高的HEV感染风险,应引起高度重视.

Objective To analyze hepatitis E prevalence and trends,to explore its epidemiological characteristics for prevention and control measures. Methods A retrospective study was used to analyze the prevalence of hepatitis E in First Affiliated Hospital of Anhui Medical University from 2010 to 2012. Results 7903 samples of hepatitis E virus antibody were detected in the First Mfiliated Hospi- tal of Anhui Medical University from 2010 to 2012. 832 samples were anti-HEV-igG positive and testing positive rate was 10.53%. 409 samples were anti-HEV-igM positive and testing positive rate was 5.18%. The proportions of hepatitis E patients in all hepatitis patients in 2010,2011 and 2012 were 2.39% ,3.67% and 3.14%, respectively. The positive rate of seruna anti-HEV-igM in people younger than 20 years old was less than 1%. The proportion of patients fi＇om 40 to 60 years old was 61.8% in all hepatitis E patients. Male patients were 3 to 4 times higher than female patients. Conclusions The results suggest that HEV-positive rate in people younger than 20 years old is vet3, low and male patients and patients from 40 to 60 years old are higher risk of HEV infection.