冲洗式泪道探通术辅以氧氟沙星治疗新生儿泪囊炎的临床分析

Clinical effect of lavaging lacrimal passage probe combined with ofloxacin on neonatorum dacryocystitis

目的探讨冲洗式泪道探通术辅以氧氟沙星治疗新生儿泪囊炎的临床疗效。方法对136例新生儿泪囊炎患儿随机分为治疗组(68例,74眼)和对照组(68例,75眼)。对照组给予冲洗式泪道探通术,治疗组给予冲洗式泪道探通术,并于术中推注氧氟沙星凝胶。观察两组患儿的治愈率、探通次数及术中并发症。结果治疗组患儿治愈率为97.3%,显著高于对照组治愈率88.0%(χ2=4.71,P<0.05);与对照组比较,治疗组一次探通成功率明显升高(χ2=4.87,P<0.05);治疗组并发症的发生率2.9%,显著低于对照组16.2%(χ2=7.03,P<0.05)。结论冲洗式泪道探通术辅以氧氟沙星治疗新生儿泪囊炎安全有效,治愈率高,重复探通率低,且并发症少。

Objective To explore clinical effect of lavaging lacrimal passage probe combined with ofloxacin on neonatorum dacryocystitis. Methods 136 neonatorum dacryocystitis were randonily divided into treatment group （68 cases,74 eyes） and control group（68 cases,75 eyes）. Control group was given lavaging lacrilnal passage probe only,while treatment group was given lavaging lacrilnal passage probe combined with ofloxacin. The cure rote, number of probing,and intraoperative complications were observed and analyzed. Results The cure rates in treatment group and control group were 97.3% ,88.0% ,respectively,which was statistically different （X2= 4.71, P 〈 0.05）. Compared with control group,the success rate by once probing was increased O（X2=4.87, P 〈 0.05）. The complications in treatment group was 2.9% ,which was statistically lower than that in control group 16.2% （X2= 7.03,P 〈 0.05）. Conclusions it is safe and effective of lavaging lacrilnal passage probe combined with ofloxaein for neonatorum,which has advantages of high cure rate, low repeating probing rate and low intraoperative complications.