清肝解毒止咳方治疗病毒感染后慢性咳嗽的临床研究

Clinical Research on QingGan JieDu ZhiKe Prescription on the Treatment of Chronic Cough after Virus Infection

目的:研究本院协定方—清肝解毒止咳方治疗病毒感染后慢性咳嗽的临床疗效。方法:采用随机对照双盲的方法,对符合研究标准的慢性咳嗽患者分为治疗组和对照组,治疗组给予以清肝解毒止咳方为基础方的中药治疗,对照组采用福莫特罗/布地奈德粉吸入剂治疗。比较两组间疗效、生活质量改善以及停药2周后咳嗽复发情况的差异性。结果:通过比较发现,在痊愈患者中,治疗组时间短于对照组(P<0.05);治疗2周后,生活质量改善方面治疗组明显优于对照组(P<0.05);停药2周后,治疗组复发率明显低于对照组(P<0.05)。结论:对于病毒感染后慢性咳嗽,以清肝解毒止咳方为基础方的协定处方在缩短病程、改善患者生活质量和控制复发率上有明显优势,值得临床推广运用。

Objective ：To investigate the curative effect of QingGan JieDu ZhiKe Prescription from Dezhou Hospital of Traditional Chi- nese Medicine on chronic cough after virus infection. Methods ： Take the method of random, contrast, double blind for research. Divid- ed patients that accorded with our research standards into treatment group and control group. Patients in the treatment group were treated by QingGan JieDu ZhiKe Prescription, meanwhile the control group was treated by budesonide and formoterol fumarate powder for inhala- tion. Differences on curing time, the improvement of symptom, living quality and the recurrence rate were compared two weeks after treatment. Results： Through comparison, treatment group took less time to be cured compared to the control group （ P 〈 0. 05 ）. After two weeks of treatment, living quality in the treatment group was better improved than that in the control group （ P 〈 0. 05）. Two weeks after the treatment was finished, recurrence rate in the treatment group was lower than that in the control group （ P 〈 0.05 ）. Conclu- sion： QingGan JieDu ZhiKe Prescription has significant advantage on course of treatment, improvement of living quality and recurrence rate control on chronic cough after virus infection. It is worth using in clinical practice.