早期急性心肌梗塞静脉溶栓治疗的临床观察

Clinical effect of intravenous thrombolysis in treatment of early acute myocardial infarction

目的观察静脉溶栓治疗早期急性心肌梗塞的临床疗效。方法随机选取我院48例心肌梗塞患者,采用尿激酶静脉溶栓治疗,对所有患者的临床治疗效率及相关资料进行回顾性分析。结果 48例急性心肌梗塞患者中,有37例患者达到再通标准,再通成功率为77.08%,11例未达到再通标准,发病后6h内进行静脉溶栓治疗的临床疗效要优于6-12h内行静脉溶栓治疗的临床疗效,两组再通成功率有差异性统计学意义(P<0.05)。结论采用尿激酶静脉溶栓治疗早期急性心肌梗塞的临床疗效显著,同时治疗后并发症发生率较低,值得临床推广。

Objective To observe the clinical effect of intravenous thrombolysis in the treatment of early acute myocardial infarction. Methods Forty-eight patients with myocardial infarction were randomly selected from our hospital to receive intravenous thrombolysis using urokinase. The treatment response rate and related data were retrospectively analyzed. Results Of the 48 patients with acute myocardial infarction, 37 met recanalization standards, with a recanalization success rate of 77.08%. The clinical effect of intravenous thrombolysis was better when performed within 6 h after onset than when performed at 6-12 h after onset. There was a significant difference in recanalization success rate between the two groups （P〈0.05）. Conclusion Intravenous thrombolysis using urokinase has a significant clinical effect and causes few complications in the treatment of early acute myocardial infarction, and it holds promise for clinical application.