慢性重型肝炎预后因素分析

Analysis of prognostic factor in chronic severe hepatitis

[目的 ] 本文研究了影响慢性重型肝炎的预后因素。 [方法 ] 运用了多元回归分析了可能影响慢性重型肝炎的 2 3项预后因素。 [结果 ] 单因素示有腹水者 ,肝脏体积越小 ,预后越差。总胆固醇、胆碱脂酶、白蛋白、凝血酶原活动度越低 ,预后越差。有肝肾综合征、肝脑综合征有出血者、自发性细菌性腹膜炎者 ,预后越差。多因素示 ,凝血酶原活动度越低 ,预后越差。 [结论 ] 本文研究提示凝血酶原活动度是影响慢性重型肝炎预后的重要因素。

Objective] To study the impact of prognostic factors in chronic severe hepatitis (CSH). [Methods] Using mutiple logistic regressive system, the impact of prognostic factors in CSH were analysised. [Results] Single factor analysis showed poor prognosis in having ascites,small liver size, hepatorenal syndrome, hepatic encephalopathy, bleeding and spontaneous bacterial peritonitis and with lowered cholesterol, cholinesterase, albumin, prothrombin activity. Multifactor analysis showed poor prognosis in lowered prothrombin activity. [Conclusion] The main risk factor of prognosis in CSH is prothrombin activity.