急性缺血性脑卒中多模式CT检查的可行性研究

Feasible analysis of multimodal CT examination in patients with acute ischemic stroke

目的建立快速安全的急性缺血性脑卒中的多模式CT检查绿色通道，并验证其可行性。方法67例2011年1月～2012年12月临床确诊的前循环急性期缺血性脑卒中患者（发病时间〈9h）。将2011年1月～2011年12月的29例患者作为对照组，均行常规CT检查，2012年1月～2012年12月的38例患者作为实验组，均行多模式CT检查。分析所有患者的一般信息，发病到接受检查的时间，检查开始到接受rt—PA治疗的时间，出血转化以及发病后7d患者的临床转归（mRS评分）。分析两组间的差异。结果实验组及对照组中，患者的一般信息，发病到接受检查的时间，检查开始到接受rt—PA治疗的时间，出血转化以及发病后7d患者的临床转归（mRS评分）的差异均无统计学意义。其中接受rt—PA治疗的患者从CT检查开始到接受rt—PA治疗的时间差异也无统计学意义。结论多模式CT检查并不会延误患者接受rt—PA治疗，具有可行性。

Objective To establish a green channel of multimodal CT examination in patients with acute ischemic stroke and demonstrate the feasibility. Methods In a total of 67 cases of acute ischemic stroke onset less than 9 hours occurred between January 2011 to November 2012, 29 of them were selected into the control group which was performed normal CT examination, while the rest 38 were collected into the experimental group which was performed multimodal CT examination. The information included time between onset and the imagination taken place, the time between the imagination and recombinant tissue plasminogen activator （rt-PA） treatment, hemorrhage transformation and modified Rankin scale in 7 days from stroke onset. Results No significant difference was found between control group and experiment group in general information, such as the time from stroke onset to imaging, the time from imaging to recombinant tissue plasminogen activator （rt-PA） treatment, hemorrhage transformation and modified Rankin scale in 7 days from stroke onset. It reflected no statistical difference in patients who had rt-PA treatment in the time from imaging to rt-PA treatment between the two groups. Conclusion Multimodal CT examination is feasible and does not adversely increase the time to rt-PA treatment in patients with acute ischemic stroke.