中西医结合治疗鹅口疮56例临床观察

Clinical observation of combination of TCM and WM in the treatment of 56 patients with thrush

目的探讨中西医结合治疗鹅口疮的临床疗效。方法将2006年1月至2010年12月确诊为鹅口疮的110例患儿分为治疗组（56例）和对照组（54例）。治疗组用碳酸氢钠溶液清洗口腔后再用中药汤剂联合治疗，每天4次；对照组用碳酸氢钠溶液清洗口腔后加用制霉菌素溶液涂抹口腔，每天3-4次。治疗4d后观察并比较两组疗效。结果治疗组疗效[89．29％（50／56）]明显优于对照组[74．07％（40／54）]，差异有统计学意义（Х^2=6．78，P〈0.05）。结论中药联合碳酸氢钠溶液治疗鹅口疮疗效明显优于碳酸氢钠溶液联合制霉菌素治疗，采用中西医结合治疗鹅口疮疗效确切．值得临床推广应用。

Objective To observe the clinical efficacy of combination of traditional Chinese medicine （TCM） and West ern medicine （WM） in treating patients with thrush. Methods A total of 110 patients, who were diagnosed as thrush from Jan- uary 2006 to December 2010, were divided into treatment group （n=56） and control group （n=54）. The treatment group was com- bined with TCM decoction four times daily after cleaning oral cavity with sodium bicarbonate solution, and the control group was added with nystatin oral solution applied the oral cavity three or four times daily after cleaning oral cavity with sodium bicarbonate solution. The efficacy after 4-day treatment in the two groups were observed and compared. Results The efficacy in the treatment group （89.29%, 50/56） was better than that in the control group （74.07%, 40/54） and the difference had statistical significance （X2=6.78,P〈0.05）. Conclusion Combination of TCM and sodium bicarbonate solution has better efficacy than combination of sodium bicarbonate solution and nystatin in the treatment of thrush. Combination of TCM and WM has significant effect in treating thrush, and it is worthy of promotion in clinic.