肝硬化患者血浆凝血酶原时间与肝功能指标分析

Analysis of Plasma Prothrombin Time and Iiver Function in The Patients With Liver Cirrhosis

目的:探讨肝硬化患者凝血酶原时间(PT)和肝功能指标:总胆汁酸(TAB)、总胆红素(TBIL)、丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)、白蛋白(ALB)的变化规律及其相关性分析。方法:用STA-R Eolution血凝分析仪检测血浆凝血酶原时间,用贝克曼AU5400全自动生化分析仪测定80例肝硬化患者肝功能指标;与对照组40例比较,并做相关性分析。结果:肝硬化患者的肝功能指标均明显高于健康对照组;血浆凝血酶原时间明显长于健康对照组;且肝硬化患者的肝功能指标与血浆凝血酶原时间呈正相关。结论:随着肝脏损伤的加重,肝功能各项指标升高且血浆凝血酶原时间延长,且两者之间呈正相关。

Objective： To explore the dependency and the change rule of prothrombin time（PTA） and liver function： TBA. TBIL. ALT. AST. ALB. in the patients with liver cirrhosis. Methods：With the STA - R Eolu- tion blood coagulation analyzer to detect PT, Beckman AU5400 automatic biochemical analyzer is used to test 80 cases of patients with cirrhosis liver function index; Compared with the control group 40 cases, and make corre- lation analysis. Results： The liver function indices of cirrhosis were significantly higher than the normal group; Plasma prothrombin time significantly longer than the normal group; And in patients with cirrhosis of liver func- tion index was positively correlated with PT. Conclusion：Ast he liver damage is aggravating, elevated liver func- tion indicators and extend plasma prothrombin time, and between the two are related