2011年医院感染常见耐药菌的分布及耐药性的临床研究

Distribution of Drug-fast Bacteria and Analgsis of Drug Resistance in Hospital Infection

目的：调查医院感染病原菌的分布及耐药谱的变迁，为临床合理选用抗菌药物提供依据。方法：回顾分析2011年1～12月住院患者中医院感染的细菌鉴定，药物试验采用琼脂扩散法敏感试验（K-B）法，分析其耐药性。结果：医院感染2841例，病原菌送检1445例，送检率达50．8％，分离出病原菌1817株，其中肺炎克雷伯菌占17．5％，铜绿假单胞菌占15．63％，大肠埃希菌占15．34％，凝固酶阴性葡萄球菌占12．16％．鲍氏不动杆菌占11．12％，金黄色葡萄球菌占6．1％等。结论：医院感染患者常见病原菌为肺炎克雷伯菌、铜绿假单胞菌、大肠埃希菌、凝固酶阴性葡萄球菌、鲍氏不动杆菌、金黄色葡萄球菌等。

Objective： To investigate distribution of olrug- fast bacteria and analgze the drug resistance m hospital infection clincal application of antibiotic. Methods： The identification of bacteria and the antibiotic sus- ceptibility detection from Janury to december in 2011were performed drug sensitivity were tested by （K - B） and the drug resistance was analyzed. Results ： The case of 年 hospital infection were 2841, 1445 sampling vate inhospital, sampling vate was 50.8 % , 1817 strains were isolatedin hospital infection. The major pathogenio bac- teria in haspital infection wer klehsieua pneumonias 17.50 %, Pseudomonas aeruginosa 15.6 %, Escherichia coli 15.34% coagu lase - ncgative staphylococci CNS 12.16%, A baumannii 11.12% MRSA 6.1% ect. Conclu- sions： KlabsieUa pneumoniae, Escherichia coli, Pseudomonas aeruginosa. Abaumannii, Enterocous spp, aureuss （MSSA and MRSA） are the most common isolates isolated from clinical specimens of hospital.