摘要
青蒿琥酯是一种重要的青蒿素类衍生物,不仅具有抗疟作用,而且能有效杀灭血吸虫童虫,预防血吸虫病。本文综述了青蒿琥酯体内、体外抗血吸虫作用、现场应用以及药物作用机制的研究进展。
Artesunate is one of important derivatives of artemisinin, which not only has well known antimalarial effect, but also can effectively against schistosomula and prevent schistosomiasis. This article reviews the research progress of artesunate against schistosome in-vitro and in-vivo, it's clinical application and possible mechanisms of drug action.
出处
《寄生虫与医学昆虫学报》
CAS
2013年第4期265-271,共7页
Acta Parasitologica et Medica Entomologica Sinica
基金
浙江省自然科学基金项目(Y2110957)
浙江省医学重点学科群项目(XKQ-010-001)
浙江省卫生高层次创新人才培养工程项目