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微小RNA在急性髓细胞白血病中的研究进展 被引量:6

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摘要 微小RNA(microRNA)是一类长度约18—25个核苷酸的非编码单链的RNA,其进入RNA诱导沉默复合体(RISC),通过碱基互补与靶基因mRNA的3’非翻译区(UTR)特异性结合,若不完全互补,通过RISC阻止靶基因mRNA的翻译;若完全互补,通过RISC降解靶基因mRNA,
作者 马秋玲 金洁
出处 《中华医学杂志》 CAS CSCD 北大核心 2014年第2期153-156,共4页 National Medical Journal of China
基金 国家自然科学基金(81070418H0812) 卫生公益性行业科研专项(201202017) 浙江省重点创新团队(2011R50015)
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