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右美托咪定联合地佐辛等用于髋关节置换术后自控镇痛效果观察 被引量:12

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摘要 目的:观察右美托咪定联合地佐辛、托烷司琼用于老年髋关节置换术后自控静脉镇痛(PCIA)的效果。方法:选择老年髋关节置换术60例,随机分为A组、B组、C组各20例。A组给予地佐辛0.8mg/kg+托烷司琼5mg,B组地佐辛0.8mg/kg+右美托咪定1ug/(kg·d)+托烷司琼5mg,C组地佐辛0.5mg/kg+右美托咪定1ug/(kg·d)+托烷司琼5mg。观察比较3组VAS评分、Ramsay评分、不良反应发生情况及患者满意度等。结果:不同时间节点VAS分值3组比较,差异不显著(P〉0.05)。B组T2~L时间节点Ramsay分值显著高于A组和C组同时间节点(P〈0.05);T1时间节点Ramsay分值3组比较,差异不显著(P〉0.05)。3组均未发生呼吸抑制和皮肤瘙痒,A组恶心、呕吐发生率显著高于B组和C组(P〈0.05),B组嗜睡发生率非常显著高于A组和C组(P〈0.01)。C组患者总满意度显著高于A组和B组(P〈0.05),A、B两组患者总满意度差异不显著(P〉0.05)。结论:右美托咪定联合地佐辛等用于老年髋关节置换术后PCIA,可降低地佐辛用量而达到满意镇痛效果,患者满意度高,且不良反应少。
机构地区 解放军第
出处 《人民军医》 2014年第2期163-165,共3页 People's Military Surgeon
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