微创钻颅术联合尼莫地平治疗脑血肿的疗效及对神经功能的影响

Effect and impact on nerve function of minimally invasive cranial drill surgery combined with nimodipine in the treatment of cerebral hematoma

目的观察微创钻颅术联合尼莫地平治疗脑血肿的临床疗效及对患者神经功能的影响,为降低脑血肿患者的残疾率及死亡率提供参考。方法将82例脑血肿患者随机分为2组。A组40例,实施微创钻颅血肿清除术治疗;B组42例,在A组治疗基础上加用尼莫地平。采用斯堪的纳维亚卒中表(SSS)及Barthel指数(BI)表评价患者神经功能及治疗效果。结果 B组总好转率为88.10%,高于A组的67.50%(P<0.05);B组血肿完全清除率为35.71%,高于A组的15.00%(P<0.05);B组治疗20 d后SSS评分、BI值为(35.62±8.57)分、(62.78±11.36),均高于A组的(26.69±8.84)分、(54.69±10.52),两组比较差异有统计学意义(P<0.05)。结论微创钻颅术联合尼莫地平治疗脑血肿,可促进血肿清除,改善神经功能,促进患者康复。

Objective To observe the effect and impact on nerve function of minimally invasive cranial drill surgery combined with nimodipine in the treatment of cerebral hematoma,and provide reference for reducing disability and death rates of cerebral hematoma. Methods 82 cases of cerebral hematoma patients were randomly divided into two groups ,40 cases in group A implemented minimally invasive cranial drill surgery, while 42 cases in group B were treated with nimodipine based on the treatment of group A, the Scandinavian Stroke table （ SSS ） and Barthel Index （BI） table were used to evaluate neurologic function and therapeutic effect. Results The total improvement rate of group B was higher than that of group A （88. 10% vs. 67. 50% ,P 〈0. 05） ;complete removal of hematoma of group B was higher than that of group A （ 35.71% vs. 15.00% , P 〈 0. 05 ） ; after 20 d treatment, SSS score and BI were （35.62±8.57） points and （62. 78±11.36） in group B, （26. 69 ±8.84） points and （54. 69 ± 10. 52） in group A, there were singnificant differences between the two groups （ P 〈 0. 05 ）. Conclusion Minimally invasive cranial drill surgery combined with nimodipine in the treatment of cerebral hematoma, can promote removal of hematoma, improve nerve function, promote the rehabilitation of patients.