不同型号大孔树脂吸附青风藤中青藤碱特性的研究

Research on Absorption of Sinomenine in Caulis Sinomenii by Different Types of Macroporous Resin

目的:研究不同型号大孔树脂对青风藤中青藤碱的吸附效果。方法:以青藤碱转移率为考察指标,对大孔树脂吸附纯化青风藤生物碱的工艺进行筛选。结果:pH2条件下AL-3树脂对青藤碱吸附和解析效果最好,pH6条件下X-5树脂吸附和解析效果最好。结论:筛选树脂应综合考虑目标化合物的性质和树脂的孔径、比表面积、极性等参数。

This article was aimed to study the absorption of sinomenine in Caulis Sinomenii by different types of macroporous resin. The transfer rate of sinomenine was used as detection index. The screening was made on the technological process of absorption and purification ＇of sinomenine by macroporous resin. The results showed that the macroporous resin AL-3 was selected with the best absorptive capacity under pH2, while the macroporous resin X-5 was selected with the best absorptive capacity under pH6. It was concluded that the selection of macroporous resin should comprehensively consider the properties of target compounds, and indexes such as aperture, specific surface area, and polarity of maeroporous resin.