摘要
目的:优选牡丹皮中丹皮酚的最佳提取工艺。方法:以丹皮酚为指标,采用正交试验法优选最佳提取工艺。结果:最佳提取工艺为加15倍量水浸泡0.5 h,蒸馏提取2.5 h,收集馏出液,冷却至室温后,4℃下析晶24 h,过滤,室温干燥48 h。结论:优选的提取工艺稳定、合理、可行,丹皮酚提取率达到80%以上。
This article was aimed to study the optimum extraction process of paeonol. The extraction yield of paeonol was taken as investigation index. And the best extraction process was screened by orthogonal experimental design. The results showed that the optimum condition of extraction process was to soak coarse powder of Paeonia suffruti-cosa into 15-fold water for 0.5 h, and then the distillation lasted for 2.5 h. The distillate was collected and cooled to room temperature. The crystallization lasted for 24 h at 4℃, and then filtered and dried for 48 h at room tempera- ture. It was concluded that the selected technology was stable, reasonable and feasible. The extraction yield of paeonol is over 80%.
出处
《世界科学技术-中医药现代化》
北大核心
2013年第9期1998-2001,共4页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
科学技术部国家重大新药创制项目(2013ZX09402203):现代中药创新集群与数字制药技术平台:王振中
关键词
牡丹皮
丹皮酚
提取工艺
正交试验
Paeonia suffruticosa, paeonol, extraction technology, orthogonal design