毛泡桐果化学成分研究

Study on Chemical Constituents of Paulownia Tomentosa Fruit

目的研究毛泡桐果实的化学成分。方法应用柱色谱方法分离和纯化,通过理化常数和波谱分析鉴定化合物的结构。结果从毛泡桐果中分离出11个化合物,其结构分别鉴定为:β-谷甾醇(Ⅰ),泡桐素(Ⅱ),熊果酸(Ⅲ),胡萝卜苷(Ⅳ),芹菜素(Ⅴ),香草酸(Ⅵ),异香草酸(Ⅶ),对羟基苯甲酸(Ⅷ),5,7,4′-三羟基-3′-甲氧基黄酮(Ⅸ),3′-甲氧基木犀草素-7-O-β-D葡萄糖苷(Ⅹ),diplacone(Ⅺ)。结论化合物Ⅵ、Ⅶ为首次从该属中分得,化合物Ⅱ、Ⅸ、Ⅹ为首次从毛泡桐果中分得。

Objective To investigate the chemical constituents of the fruit of Paulownia tomentosa. Methods The compounds were isolated and purified by column chromatography and their structures were identified on the basis of physicochemical properties and spectral analysis. Results Eleven compounds were isolated and their structures were identified asβ-sitosterol （Ⅰ）, paulownin （Ⅱ）, ursolic acid （Ⅲ）, daucosterol （Ⅳ）, apigenin （Ⅴ）, vanillic acid （Ⅵ）, isovanillic acid （Ⅶ）, 4-hydroxybenzoic acid （Ⅷ）, 5,7,4＆#39;-trihydroxy-3＆#39;-methoxyflavone （Ⅸ）, 3＆#39;-methoxyluteolin-7-O-β-D-glucoside （Ⅹ）, diplacone （Ⅺ） . Conclusion CompoundsⅥandⅦwere isolated from the Paulownia genus for the first time. CompoundsⅡ,Ⅸ, andⅩwere isolated from the fruits of Paulownia tomentosa for the first time.