305例初发急性白血病患者各亚型及年龄组构成比的研究

Research on constituent ratios of subtypes in different age groups of 305 acute leukemia patients

目的研究急性白血病患者各亚型和年龄组构成比的关系。方法对305例初发急性白血病患者的亚型和年龄进行统计分析。结果青少年组,青壮年组,中老年组发病率分别是12.5%(38/305),39.3%(120/305),48.2%(147/305)。急性淋巴细胞白血病(ALL):青少年组发病占63.2%,中老年组发病比例仅6.1%;急性髓系白血病(AML):中老年组发病比例占55.1%,青少年组发病率最低是5.8%。M5发病较为集中在中老年组,M3主要集中在青壮年组。ALL-L2和AML-M2高发于各年龄段。结论急性白血病患者各亚型和年龄组构成比之间关系的研究,对疾病的诊断治疗有重要的应用价值。

Objective To study the relationship between the subtypes of acute leukemia and the constituent ratio of the age groups. Methods Three hundred and five incipient acute leukemia patients were conducted statistical analysis on subtypes and age. Results The incidence rates of acute leukemia were 12.5% （38/305）, 39.3% （ 120/305 ）, 48.2% （147/305） in teenagers group, adults group and middle - to - old - age group. Teenagers took about 63.2% in the morbidity of All whereas mid- die - to - old - aged group only took about 6.1% ; As to AML, the middle - to - old - aged population accounted for 55.1%, while the proportion of teenagers was 5.8%. The morbidity of M5 was high in the middle - to - old - aged group and that of M3 was high in theteenagers group. ALL- L2 and AML- M2 occuurred frequently＇ in each age group. Conclusion The research on the constituent ratios of subtypes in different age groups has significant clinical value in the etiological diagnosis and treatment of acute leukemia.