射频消融治疗肝癌的疗效

The short- term effect of radio-frequency ablation on liver cancer

目的评价肝癌患者射频消融治疗的近期疗效。方法分析接受射频消融并获得随访的46例肝癌患者的临床资料。46例肝癌患者共56处病灶接受射频消融治疗,术后1个月行超声造影及肝脏增强CT、血清肿瘤标志物检测,之后定期随访、计算术后生存率。结果 46例患者中35例病灶完全消融;25例术前AFP升高的原发性肝癌患者21例AFP下降,其中17例降至正常。术后1、2、3年生存率为86.96%、58.69%与36.75%。结论射频消融治疗肝癌具有安全、微创等特点,尤其对小肝癌疗效更佳。

Objective To evaluate the short-term effect of radio-frequency ablation on liver cancer. Methods The clinical data of 46 patients by follow-up visit with liver cancer who selected radio-frequency ablation（RFA） between January 2010 and November 2012 were analyzed retrospectively. A total of 56 lesions in 46 cases of patients were treated with RFA. The therapeutic effects were compared with con- trast-enhanced uhrasonography, contrast enhanced computed tomography and serum tumor markers detection one month after the RFA , as well as survival rate. Results Thirty-five lesions of 46 cases were fully damaged with cystic change, and no blood flow was found. Twenty-five pa- tients with significantly increased blood AFP before treatment were decreased significantly after treatment, 17 patients in which dropped to normal. The 1,2,3-year overall survival rate was 86.96% ,58.69% ,36.75%, respectively. Conclusion RFA is safe and minimally inva- sire as well as effective treatment of liver cancer in particular for small liver cancer.