摘要
通过芳香醛、达米酮和乙醇胺的＂一锅法＂无溶剂反应将羟乙基引入吖啶二酮的氮原子上,合成了一系列新型的吖啶二酮衍生物,收率29%~83%,其结构经1H NMR,13C NMR,IR和MS表征。并对其反应机理进行推测。
A series of novel 9-subsituted-decahydroacridine-1,8-dione derivatives in yield of 29% ~ 83% were synthesized by＂one-pot＂method of aromatic aldehydes,dimedione and ethanol amine under solvent-free conditions. The structures were characterized by1H NMR,13C NMR,IR and MS. The reaction mechanism was proposed.
出处
《合成化学》
CAS
CSCD
北大核心
2014年第1期24-29,45,共7页
Chinese Journal of Synthetic Chemistry
基金
国家自然科学基金资助项目(20902039,21202011)
关键词
芳醛
达米酮
乙醇胺
吖啶二酮
“一锅法”
无溶剂合成
aromatic aldehyde
decahydroacridine
ethanol amine
acridinedione
＂one-pot＂
solvent-free synthesis
