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3β,5α-二羟基-16-孕甾烯-6,20-二酮-3-糠酸酯的合成

Synthesis of 3β,5α-Dihydroxy-16-pregnene-6,20-dione-3-furoate
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摘要 以妊娠双烯醇酮醋酸酯和糠酸为原料,经环氧化、开环、水解和酯化4步反应合成了新化合物——3β-羟基孕甾烯酮糠酸酯,其结构经1H NMR,13C NMR,IR和MS表征。 A new steroid,3β,5α-dihydroxy-16-pregnene-6,20-dione-3-furoate,was synthesized by epoxidation,ring-opening,hydrolysis and esterification reaction with 16-dehydropregnenolone acetate and furoic acid as the starting materials. The structures were characterized by1H NMR,13C NMR, IR and MS.
作者 王宇龙 李洪启 于辉 杨茜茜
机构地区 东华大学化学化工与生物工程学院生态纺织教育部重点实验室
出处 《合成化学》 CAS CSCD 北大核心 2014年第1期60-62,67,共4页 Chinese Journal of Synthetic Chemistry
基金 中央高校基本科研业务费专项资金资助项目
关键词 妊娠双烯醇酮醋酸酯 孕甾烯酮 糠酸酯 酯化 合成 16-dehydropregnenolone acetate pregnenolone furoate esterification synthesis
分类号 O629.2 [理学—有机化学]
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参考文献19

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合成化学
2014年 第1期

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