豆纹动脉供血区巨大腔隙梗死6例报告(附文献复习)

Report of 6 cases and literature review on giant lacuna infarction in the lenticulostriate arterial territory

摘要目的：探讨脑豆纹动脉供血区巨大腔隙性梗死的定义、发病机制、临床和影像学特点，并与腔隙性脑梗死相鉴别。方法：分析6例豆纹动脉供血区巨大腔隙梗死患者的临床表现、实验室和影像学特征，并结合文献复习进行研究。结果：6例患者头颅MRI均显示基底节区、放射冠、半卵圆中心连续3～7个层面新鲜梗死灶。病灶长径1．9～4．0cm，符合豆纹动脉供血区巨大腔隙的诊断。结论：巨大腔隙的机制、病因、治疗及预后均不同于经典的腔隙性脑梗死，对影像表现为豆纹动脉供血区梗死的病例，应鉴别巨大腔隙与腔隙性脑梗死，有利于进一步治疗和判断预后。

Abstract Objective：To investigate the definition,pathogenesis,clinical features and imaging characteristics of giant lacuna infarction in the lenticulostriate arterial territory,and distinguish it with lacunar infarction,in order to improve the understanding of this disease.Methods：The clinical manifestations,laboratory and imaging fea- tures of 6 cases of giant lacuna infarction in the lenticulostriate arterial territory were analyzed and the litera- ture was reviewed.Results ：The 6 cases showed continuous 3-7 sections and major axis 1.9-4.0cm of fresh in- farcts in basial ganglion,corona radiate and the region besides the lateral ventricle ,conforming to the diagnosis of giant lacuna infarction in the lenticulostriate arterial territory.Conclusion：The pathogenesis,causes,treatment and prognosis of giant lacuna infarction were different from lacunar infarction.As to the cases of cerebral in- farction in the lentieulostriate arterial territory,giant lacuna infarction should be suspected and differentiated from lacunar infarction to direct further treatment and judge prognosis.