子宫内膜癌150例临床病例分析

Clinical Analysis of 150 Cases with Endometrial Carcinoma

目的:探讨与子宫内膜癌术后生存率相关的因素。方法:选择2004年2月-2011年12月北京朝阳医院经手术治疗术后病理确诊为子宫内膜癌的患者150例,分析与子宫内膜癌术后生存率相关因素。结果:年龄大于等于56岁的患者3年、5年生存率低于年龄小于56岁的患者(P<0.05);早期(Ⅰ期、Ⅱ期)患者的3年、5年生存率明显高于晚期(Ⅲ期、Ⅳ期)患者(P<0.05);组织分化较好的(G1、G2)患者的3年、5年生存率高于组织分化差的(G3)患者(P<0.05);肌层浸润深度小于1/2的患者的3年、5年生存率高于肌层浸润深度大于等于1/2的患者(P<0.05)。结论:子宫内膜癌术后患者的生存率与年龄、手术-病理分期、组织分化、肿瘤肌层浸润深度密切相关。故早期发现并诊治子宫内膜癌能明显提高患者术后生存率。

Objective：To explore the factors related to postoperative survival rate of endometrial carcinoma.Method：A total of 150 patients with endometrial carcinoma underwent primary surgical treatment and confirmed by pathology from Feb 2004 to Dec 2011 in Beijing Chaoyang Hospital were selected, and the factors related to postoperative survival rate of endometrial carcinoma were analyzed.Result：The postoperative survival rates in 3 and 5 years of patients whose ages were greater than or equal to 56 years-old were lower than that of patients whose ages were less than 56 years-old（P＆lt;0.05）.The postoperative survival rates in 3 and 5 years of patients in the early stage（phaseⅠand phaseⅡ） were higher than that of patients in the latter period（P＆lt;0.05）.The postoperative survival rates in 3 and 5 years of patients whose degrees of tissues differentiation（G1 and G2） were better were higher than that of patients whose degrees of tissues differentiation（G3） were bad（P＆lt;0.05）.The postoperative survival rates in 3 and 5 years of patients whose muscular infiltration depth were less than 1/2 were higher than that of patients whose muscular infiltration depth were greater than or equal to 1/2（P＆lt;0.05）.Conclusion：Age,surgical-pathologic stage,tissue differentiation and the depth of tumor invasion are closely related to the postoperative survival rate of patients with endometrial carcinoma.So early discovery,early diagnosis and early treatment of patients with endometrial carcinoma can raise the postoperative survival rate.