78例高脂血症性急性胰腺炎的临床特征分析

目的总结及分析高脂血症性急性胰腺炎（HLAP）的临床特征，以提高对该病的认识及诊治水平。方法选取2008年4月至2013年7N78例HLAP患者作为观察组，并随机选取80例胆源性急性胰腺炎（BAP）患者作为对照组，对病史资料进行回顾性分析。结果相对于BAP组，HLAP组平均年龄低，血清淀粉酶、CRP水平低，血清三酰甘油水平、胆固醇水平、合并脂肪肝、糖尿病比例均显著高于BAP组（P〈0．05）。HLAP组重度患者较BAP组少，但是复发率高（P〈0．05）。结论本研究中HLAP患者发病年龄低，合并脂肪肝、糖尿病者多，血清淀粉酶升高不显著，轻度患者多，AP易复发。

Objective To summarize and analysis the clinical characteristics of hyperlipidemic acute pancreatitis （ HLAP ） for improving the understanding diagnostic and therapeutic performance of this disease. Methods 78 patients diagnosed with HLAP at the First Affiliated Hospital of Soochow University from April 2008 to July 2013 were selected as experimental group; 80 cases of BAP at the corresponding period in our hospital were selected as the control group. All of those clinical data were retrospectively analyzed. Results Compared to BAP group, the mean age was significantly lower in HLAP group. The serum levels of amylase and CRP were lower in HLAP group than in BAP group. The serum levels of triacylglycerol and cholesterol were significantly higher in HLAP group than in BAP group. Much more cases in HLAP group were complicated with fatty liver, diabetes while compared with BAP group （ P〈0.05 ） . The number of SAP patients in HLAP group was much fewer than in BAP group, but the recurrence rate was significantly higher in HLAP group than in BAP group （ P〈0.05 ） . Conclusions Patients with HLAP are significantly younger and most of them are complicated with fatty liver or diabetes. Serum amylase is minimally elevated. The MAP rate and recurrence rate is much higher in HLAP patients.