极低出生体重儿早期微量喂养与坏死性小肠结肠炎发生率相关性研究

The analysis of early minimal feeding in very low birth weight infants and the pertinecy of necrotizing enterocolitis

目的:探讨极低出生体重儿早期微量喂养与新生儿坏死性小肠结肠炎(NEC)的相关性。方法:选择2009年1月—2012年8月收治的极低出生体重儿136例,随机分为对照组63例和实验组73例。实验组在出生后24 h内即开始微量喂养,对照组在出生后72 h后开始微量喂养,并根据喂养耐受情况逐渐增加奶量,比较3周内两组NEC的发生率。采用χ2检验进行统计学分析。结果:治疗组发生NEC的概率为6.8%,对照组发生NEC的概率为7.9%,治疗组的NEC发生率与对照组比较差异无统计学意义(P>0.05)。结论:本研究显示对极低出生体重儿24 h内开始微量喂养及生后72 h后开始微量喂养,其NEC发生率比较差异无统计学意义。

Objective ： To investigatd the early feedings correlation with necrosis of the small intestine enterocolitis （NEC） in very low birth weight infants. Methods：The object of study for 136 very low birth weight infants admitted to hospital from January 2009 to August 2012 meet the diagnostic criteria for very low birth weight infants. They were divided into control and experimental groups randomly. 63 cases were assighned to the control group,73 cases were assighned to the treatment group. Experimental group started feedings within 24 hours after birth, the control group were started in 72 hours after birth, and accor-ing feeding tolerance gradually grow milk, 10 - 20 mE · kg^-l · d^-1 ,comparing the two groups NEC situation occurred, in three weeks. X2 test was used for statistical analysis. Results：The probability of the treatment group occurred NEC 6.8 % ,7.9% in the control group, NEC incidence with the control group of the treatment group, no significant difference （ P 〉 0.05 ）. Conclu- sion：This study shows that after feedings in 72 hours after the 24 hours of very low birth weight infants fed groups began to trace and health group, NEC incidence did not have significantly difference.