2012～2013年合肥地区孕妇OGTT筛查结果分析

The analysis of OGTT screening results of pregnant women in Hefei area from2012 to 2013

目的：调查合肥地区孕妇妊娠期糖代谢异常的发生率，探讨其相关高危因素，以及孕妇在妊娠期进行口服葡萄糖耐量试验（OGTT）筛查的意义。方法以1520例2012～2013年于该院门诊就诊的妊娠前无糖尿病、高血压、心脏病、肾脏疾病、血液系统疾病及其他系统疾病的孕妇为研究对象，进行75 g OGTT筛查，结合临床相关资料分析合肥地区孕妇妊娠期糖代谢异常发生的相关高危因素。结果1520例孕妇75 g OGTT筛查阳性率为5．78％，其中葡萄糖耐量降低发生率为2．50％，妊娠糖尿病（GDM）检出率为3．28％。高龄、孕前肥胖及糖尿病家族史为妊娠期孕妇糖代谢异常的相关高危因素。结论对孕妇进行OGTT筛查能够有效发现GDM高危孕妇，并可及早预防和减少GDM的相关并发症。

Objective To investigate the occurrence of glucose metabolism abnormality in pregnant women in Hefei area and its related risk factors,as well as the significance of oral glucose tolerance test（OGTT） during pregnancy. Methods From 2012 to 2013,1 520 cases of pregnant women treated in the hospital were enrolled in the study, those patients with diabetes, hypertension, heart disease,kidney disease,blood diseases and other system diseases were excluded. A 75 g OGTT was employed in the screening, and related clinical data were analyzed to explore the risk factors of glucose metabolism abnormality. Results The positive rate of 1 520 cases of pregnant women in 75 g OGTT was 5.78% ,the rate of glucose tolerance reduce was 2.50%,the detection rate of gestational diabetes mellitus （GDM） was 3.28 %. Age,overweight before pregnancy, family history of obesity and diabetes are risk factors of abnormal glucose metabolism during pregnancy. Conclusion The OGTT screening in pregnant women can effectively de- tect pregnant women with high risk of GDM,and it can contribute to early prevention and reduction of GDM related complications.