河南省普通人群丙型肝炎感染的相关因素

A cross-sectional study on related factors associated with hepatitis C among general population in Henan Province

目的了解现阶段河南省普通人群的丙型肝炎感染的相关因素。方法采用横断面调查的方法，于2012年4—7月，采取多阶段抽样的方法，选择全省30个项目县（区）1—75周岁的常住居民开展问卷调查，采集静脉血，并检测HCV抗体和核酸。结果共调查32203人，多因素Logistic回归分析显示，既往有偿采供血史（OR=11．60，95％CI：6．56～20．52）、输血史（OR=5．97，95％CI：3．71～9．60）、纹身（OR=2．66，95％CI：1．37～5．17）、不规范注射行为（OR=1．93，95％CI：1．29～2．90）和手术史（OR；1．82，95％CI：1．25～2．65）是感染丙肝的相关因素。结论为减少丙肝传播，应继续开展无偿献血和血液安全筛查，严格遵守卫生学标准开展卫生诊疗服务，普及丙肝防治知识，倡导积极健康的生活方式。

Objective To explore the related factors associated with hepatitis C among general population in Henan Province. Methods A cross-sectional survey was carried out from April to July 2012. A multi-stage sampling was utilized and finally 30 districts were chosen. Questionnaires were administrated among general population aged 1-75 years. Blood samples were collected and tested for anti-HCV and hepatitis C virus. Results 32 203 persons were investigated. Multivariate Logistic regression analysis showed that related factors including： history of formal plasma denotation, blood transfusion, tattooing, non-standard injection behavior and operation. Adjusted ORs and confidence ijitervals of them 11.60 （6. 56-20. 52）, 5.97 （ 3.71-9. 60 ）, 2. 66 （ 1.37-5.17 ）, 1.93 （ 1.29-2. 90 ）, 1.82 （ 1.25-2. 65 ） respectively. Conclu- sions It is necessary to continually carry out blood donation and blood security screening, strictly comply with the hygiene standards through health care service, and disseminate knowledge of prevention and treatment of hepatitis C, together with advocating a healthy lifestyle in order to. reduce HCV transmission.