间苯三酚对分娩产程的促进作用

Acceerative efficacy of phloroglucinol in the childbirth process

目的观察间苯三酚对于分娩产程的促进作用。方法选择我科自2012年l～12月收治的行阴道分娩的足月初产妇88例，随机分为观察组和对照组各44例，观察组静脉注射问苯三酚80mg，对照组不使用任何药物进行干预。观察两组产程中各指标及新生儿情况。结果与对照组比较，观察组潜伏期和活跃期时间较少，宫口扩张速度较快而疼痛强度较轻，新生儿窘迫率和产妇宫颈水肿的发生率均较低，剖宫产率／阴道分娩率明显低于／高于对照组，差异具有显著或者非常显著性意义（P〈0．05或P〈0．01）。结论间苯三酚可以有效缩短产妇的第一产程，加快宫口扩张速度，且对产妇和胎儿无明显的不良反应，值得在临床推广使用。

Objective To observe the acceerative efficacy of Phloroglucinol in the childbirth process. Methods A total of 88 cases healthy and normal primiparas in our department from January to December 2012 were selected and they were divided into observation group and control group randomly, each of 44 cases. The observation group underwent phloroglucinol injection with 80 mg and the control group was not given any drug intervention. Indexes in the pregnant women stages of labor and neonatal condition between two groups were compared. Results Compared to control group, the time of incubation and active phase stage of childbirth process was shorter in observation group, and speed of miyaguehi expansion was significantly higher, the newborn suffocation and cervical edema incidence were significantly lower. The cesarean section rate/vaginal delivery rate was significantly lower/higher （P 〈 0.05 or P〈0.01）. Conclusion Phloroglucinol can effectively accelerate progress in childbirth process and miyaguchi expansion speed and has no bad influence on maternal and child. It is worthy of clinical use.